Lipids and Lipid Derivatives
Medchemexpress LLC (±)-Abscisic acid | 14375-45-2 | 5 MG
(±)-Abscisic acid is an orally active plant hormone that is also present in animals. It contributes to the regulation of glycemia in mammals. For research use only, not for sale to patients.
Selleck Chemical LLC Ribociclib succinate S5188-10mM/1mL
Ribociclib (LEE011) succinate is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM respectively
Medchemexpress LLC Bazedoxifene (acetate)-D | 198481-33-3 | C32H38N2O5 | 5 MG
Bazedoxifene (acetate)-D is the D-crystal form compound of Bazedoxifene acetate, an orally active, nonsteroidal selective estrogen receptor modulator (SERM). It targets the Estrogen Receptor/ERR pathway, specifically the Vitamin D Related/Nuclear Receptor, with IC50s of 23 nM for ERα and 99 nM for ERβ.
- D-crystal form compound
- Orally active, nonsteroidal selective estrogen receptor modulator (SERM)
- Targets estrogen receptor/ERR
- Part of vitamin D related/nuclear receptor pathway
- IC50s of 23 nM for ERα and 99 nM for ERβ
Medchemexpress LLC Paclitaxel | 33069-62-4 | C47H51NO14 | 1 G
Paclitaxel is a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. It can induce mitotic arrest and apoptotic cell death, and also autophagy.
- Stabilizes tubulin polymerization
- Induces mitotic arrest
- Induces apoptotic cell death
- Induces autophagy
- Used in cardiovascular disease research
- Used in cancer research
Medchemexpress LLC Palonosetron-d3 hydrochloride | 1246816-81-8 | C19H22D3ClN2O | 1 MG
Palonosetron-d3 hydrochloride is the deuterium-labeled Palonosetron hydrochloride. Palonosetron hydrochloride acts as a 5-HT3 antagonist, primarily utilized for the prevention of acute, delayed, and overall chemotherapy-induced nausea and vomiting. Additionally, it exhibits moderate anti-flavivirus activity and potent anti-Zika virus activity in mammalian cells. Palonosetron hydrochloride also has antidepressant activity.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Verapamil-d3 hydrochloride | 2714485-49-9 | 99.57% | C27H36D3ClN2O4 | 5 MG
Verapamil-d3 hydrochloride is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride is a calcium channel blocker and a potent, orally active first-generation P-glycoprotein (P-gp) inhibitor. It also inhibits CYP3A4 and has potential for research into high blood pressure, heart arrhythmias, and angina.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Cholesteryl oleate-d7 | 1416275-35-8 | 99% | 658.14 | 1 MG
Cholesteryl oleate-d7 | 1416275-35-8 | 99% | 658.14 | 1 MG
Medchemexpress LLC Propionylcarnitine | 17298-37-2 | 98.0% | 217.26 | 1 MG
Propionylcarnitine is metabolized by carnitine acetyltransferase from propionyl-CoA. Increased propionylcarnitine is considered a biomarker of vitamin B12 deficiency. This product is intended for research use only.
- Human endogenous metabolite
- Protection of beta-thalassaemic erythrocytes from oxidative stress
- Increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl carnitine from pyruvate
- Allows endothelial cells to maintain functionality and regulatory role on vessel activity for a longer time, and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine
- Affects plasma and urine total carnitine concentrations of mice (2 mM/kg; p.o. for 4 weeks)
Medchemexpress LLC Propionylcarnitine | 17298-37-2 | 98.0% | 217.26 | 10 MG
Propionylcarnitine is metabolized by carnitine acetyltransferase from propionyl-CoA. Increased propionylcarnitine is regarded as a biomarker of vitamin B12 deficiency.
- Regarded as a biomarker of vitamin B12 deficiency.
- Shows protection to beta-thalassaemic erythrocytes from oxidative stress.
- Increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl carnitine from pyruvate.
- Allows endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time, and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism.
Medchemexpress LLC Palmitoylcarnitine | 1935-18-8 | MFCD00152152 | 100.0% | 399.61 g/mol | C23H45NO4 | 5MG
Palmitoylcarnitine is an endogenous O-acylcarnitine metabolite used as a research reagent and reference standard in studies of fatty acid metabolism and mitochondrial function. It is supplied as a solid powder with high stated purity and recommended low-temperature storage for long-term stability.
- High purity suitable for analytical applications.
- Solid powder form for easy handling and weighing.
- Available in small research sizes, including 5 mg.
- Stable when stored at low temperatures for extended periods.
- Provides a standard for metabolic and biochemical assays.
Medchemexpress LLC Octanoyl-L-carnitine | 25243-95-2 | MFCD28580111 | ≥99.0% | 287.40 g/mol | C15H29NO4 | 5 MG
L-Octanoylcarnitine is an endogenous human plasma metabolite and the physiologically active O-octanoyl ester of L-carnitine supplied for research use. It is provided as a white to off-white solid and is used in studies of fatty acid metabolism and cancer research, including breast cancer investigations.
- CAS number 25243-95-2.
- Molecular formula C15H29NO4; molecular weight 287.40 g/mol.
- Purity ≥99.0%.
- Soluble in DMSO at about 100 mg/mL with ultrasonic aid; example in vivo formulations yield ≥2.5 mg/mL.
- Physical form white to off-white solid; hygroscopic DMSO affects solubility.
- Intended for research applications in endogenous metabolism and cancer studies.
Medchemexpress LLC Isovalerylcarnitine chloride | 139144-12-0 | 99.48% | C12H24ClNO4 | 50 MG
Isovalerylcarnitine chloride is a leucine metabolite that specifically activates human neutrophil calpain. Elevated circulating levels are inversely associated with a reduced risk of lung cancer. This product is for research use only and not sold to patients. It also acts as a selective activator of calpain, inducing apoptosis.
- Metabolite of leucine
- Activates human neutrophil calpain
- Associated with reduced risk of lung cancer
- Induces apoptosis
eMolecules 1334532-19-2 | Medchem Express | Levocarnitine propionate-d3 (hydrochloride) | 1mg | 742367797 | HY-B0932S | 256.74 | C10H20ClNO4
Medchem Express | CCT-251921 | 1mg | 446270680 | HY-19984 | 1607837-31-9 | MFCD30502895 | 410.910 | C21H23ClN6O
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Medchemexpress LLC L-Hexanoylcarnitine-d3 chloride | 2483831-95-2 | 99.0% | 298.82 | 1 MG
L-Hexanoylcarnitine-d3 (chloride) is a deuterium labeled compound designed for quantitative analysis. It serves as a tracer or an internal standard in various analytical techniques.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS